Supporting Materials

Diagnosit® BVBLUE®

Diagnosit® BVBLUE® Control Kit

Marketing Materials

References:

Clinical Performance of Diagnosit® BVBLUE®:

  • Gag, ZG.F.M. et al. 2014. Evaluation of different diagnostic methods of bacterial vaginosis. J. Dental Med. Sci. 13: 15. http://iosrjournals.org/iosr-jdms/papers/Vol13-issue1/Version-8/D013181523.pdf
  • 2014. The Point of Care Test Health Essay. UKessays.  http://www.ukessays.com/essays/health/the-point-of-care-test-health-essay.php
  • Kampan, N.C. et al.  2011. Evaluation of BVBLUE® Test Kit for the diagnosis of bacterial vaginosis. Sex. Reproduct. Healthcare 2: 1. URL: http://www.sciencedirect.com/science/article/pii/S1877575610000790
  • Shujatullah, F. et al. 2010. An evaluation of OSOM BVBLUE® test in the diagnosis of bacterial vaginosis. Asian J. Trop. Med. 3: 574. URL: http://www.sciencedirect.com/science/article/pii/S1995764510601393
  • Akhter, S. et al. 2010. Rapid detection of Bacterial Vaginosis (BV) by BVBLUE® test. Bangladesh J. Med. Microbiol. 4: 24.  URL: http://www.banglajol.info/index.php/BJMM/article/view/8465
  • Anukam, K. et al. 2006. Augmentation of antimicrobial metronidazole therapy of bacterial vaginosis with oral probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14: randomized, double-blind, plaebo controlled trial. Microbes and infection 8: 1450e.
  • Sumeksri, P. et al. 2005. BVBLUE® test for diagnosis of bacterial vaginosis in pregnant women attending antenatal care at Phramongkutklao Hospital. J. Med. Assoc. Thailand 88:S7.  URL: http://www.scopus.com/record/display.url?eid=2-s2.0-33749048743&origin=inward&txGid=2F95611692479A404845D3BFCF16DAA3.aqHV0EoE4xlIF3hgVWgA%3a2
  • Bradshaw, C.S. et al. 2005. Evaluation of point-of-care test, Diagnosit® BVBLUE®, and clinical and laboratory criteria for diagnosis of bacterial vaginosis. J. Clin. Microbiol. 43:1304.
  • Myziuk, L. et al. 2003. Diagnosit® BVBLUE® test for diagnosis of bacterial vaginosis. J. Clin. Microbiol. 41:1925.
  • McGregor, J.A. et al. 2003. Quantitative vaginal fluid sialidase (Diagnosit® BVBLUE®) correlates with Nugent’s Score vaginal gram stain testing in symptomatic women. Presented at Infectious Disease Society for Obstetrics and Gynecology (IDSOG). Hyannis, MA. USA.
  • McGregor, J.A. et al. 2002. Assessing vaginal fluid sialidases in women with bacterial vaginosis (BV). Presented at Infectious Disease Society for Obstetrics and Gynecology (IDSOG). Banff, Alberta, Canada.
  • McGregor, J.A. et al. 2002. Vaginal fluid concentration of sialidase (neurominidase) correlation with common vaginal conditions. Presented at Infectious Disease Society for Obstetrics and Gynecology (IDSOG). Banff, Alberta, Canada.
  • Johnson, S.C. et al. 2002. Clinical performance of the Diagnosit® BVBLUE® test for evaluation of vaginal fluid sialidase activity and its diagnostic value for evaluation of bacterial vaginosis. Clin. Chem. 48:A191.
  • Myziuk, L. et al. 2002. Comparison of Diagnosit® BVBLUE® to standard methodology for diagnosing bacterial vaginosis. Presented at American Association for Microbiology (ASM). Salt Lake City, UT, USA.
  • McGregor, J.A. et al. 2000. Vaginal fluid sialidase enzyme activity in patients with positive Diagnosit® BVBLUE® test, candidiasis, trichomoniasis, and in healthy controls. Presented at Third International Meeting on Bacterial Vaginosis. Ystad, Sweden.
  • French, J.I. et al. 2000. Point of care diagnosis of bacterial vaginosis by analysis of Diagnosit® BVBLUE®, Amsel’s criteria, and gram’s stain. Presented at Third International Meeting on Bacterial Vaginosis. Ystad, Sweden.

Elevated sialidase activity in patients with Bacterial Vaginosis:

  • Cauci, S. et al. 2003. Determination of Immunoglobin A against Gardnerella vaginalis hemolysin, sialidase, and prolidase activities in vaginal fluid. Implications for adverse pregnancy outcomes. J. Clin. Microbiol. 41:435.
  • Cauci, s. et al. 2002. Correlation of local interleukin-8 with Immunoglobin A against Gardnerella vaginalis hemolysin and with prolidase and sialidase levels in women with bacterial vaginosis. J. Infect. Dis. 185:1614.
  • Smayevsky, J. et al. 2001. Vaginal microflora associated with bacterial vaginosis in nonpregnant women: reliability of sialidase detection. Infect. Dis. Obstet. Gynecol. 9:17.
  • Wiggins, R. et al. 2001. Mucinases and sialidases: their role in the pathogenesis of sexually transmitted infections in the female genital tract. Sex. Transm. Infect. 77:402.
  • Cauci, S. et al. 1998. Immunoglobulin A response against Gardnerella vaginalis hemolysin and sialidase activity in bacterial vaginosis. Am. J. Obstet. Gynecol. 178:511.
  • McGregor, J.A. et al. 1994. Bacterial vaginosis is associated with prematurity and vaginal fluid mucinase and sialidase: results of a controlled trial of topical clindamycin cream. Am. J. Obstet. Gynecol. 170:1048.

Elevated sialidase activity in isolates of Gardnerella vaginalis, Bacteroides spp., Prevotella spp., and Mobiluncus spp.:

  • Briselden, A. et al. 1992. Sialidases (neuraminidases) in bacterial vaginosis and bacterial vaginosis-associated microflora. J. Clin. Microbiol. 30:663.
  • Moncla, B.J. et al. 1990. Sialidase (neuraminidase) activity among gram-negative anaerobic and capnophilic bacteria. J. Clin. Microbiol. 28:422.